A Study of Rofecoxib in the Treatment of Post-Operative Pain After Total Knee Joint Replacement (0966-259)

Phase 4

Terminated

• Conditions: Pain

• Registration Number: NCT00140920
• Lead Sponsor: Merck Sharp & Dohme LLC

Brief Summary

A study to compare pre-operative administration of rofecoxib versus post-operative administration of diclofenac or rofecoxib, respectively, in the treatment of post-operative pain after total knee joint replacement in patients with osteoarthritis of the knee.

Detailed Description

Not available

Study Timeline

• Study Start: 2004-05-25
• Primary Completion: 2004-09-27
• Study Completion: 2004-09-27
• Study First Submitted: 2005-08-30
• Study First Submitted QC: 2005-08-30
• Study First Posted: 2005-09-01
• Status Verified: 2017-05
• Last Update Submitted: 2017-05-05
• Last Update Posted: 2017-05-09

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 11

Inclusion Criteria

• Males or females at least 18 years of age who have osteoarthritis of the knee and have undergone total knee joint replacement.

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Quantity of patient controlled
Post-operative morphine administration