NCT00858702已完成4 期
Add-on Study of CCBs or Diuretics in Essential Hypertension Not Achieving Target Blood Pressure on Olmesartan Medoxomil Alone
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 105
- 主要终点
- The Percentage of Patients Achieving Target Sitting Blood Pressure of Less Than 130/85
研究概览
简要总结
The purpose of the study is to test the efficacy and safety of the combination of Calcium Channel Blockers (CCBs)(of the dihydropyridine class) or Diuretics (of the thiazide class) and olmesartan medoxomil in essential hypertensive patients whose blood pressure is not adequately controlled with olmesartan medoxomil alone
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 74 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Mean seated blood pressure greater than or equal to 140/90 mmHg under circumstances in pre-treatment with olmesartan medoxomil
- •Mean 24-hour blood pressure evaluated by ambulatory blood pressure monitoring greater than or equal to 135/80 mmHg under circumstances in pre-treatment with olmesartan medoxomil
排除标准
- •Patients with secondary hypertension
- •Any serious disorder which may limit the ability to evaluate the efficacy or safety of the test drugs
研究组 & 干预措施
1
Experimental
olmesartan medoxomil tablets and a CCB tablet (of the dihydropyridine class), once daily for 8 weeks
干预措施: olmesartan medoxomil and a CCB (Drug)
2
Experimental
olmesartan medoxomil and a diuretic tablet (of the thiazide class)
干预措施: olmesartan medoxomil and a diuretic (Drug)
结局指标
主要结局
The Percentage of Patients Achieving Target Sitting Blood Pressure of Less Than 130/85
时间窗: Baseline to week 8
次要结局
- Percentage of Patients With Drug-related Adverse Events (Subjective Symptoms/Objective Findings)(At week 8)
- Percent of Patients With Drug-related Adverse Events (Laboratory Changes in Clinical Laboratory Values)(At week 8)
研究者
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