Cognitive Adverse Effects and Efficacy of Brief Pulse and Ultra Brief Pulse ECT in Patients of Schizophrenia: A Single Blind Randomized Controlled Trial

Central Institute Of Psychiatry Kanke Ranchi0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

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•1. Diagnosis of Schizophrenia using Diagnostic Criteria for Research (DCR) of International
•Classification of Disease-10th edition (ICD-10, World Health Organization,1992)
•2. Age between 18- 60 years of either sex
•3. Calgary Depression Scale for Schizophrenia (CDSS) score less than 7
•4. Patients meeting any of the indications of ECT in Schizophrenia (Treatment Guidelines of
•Indian Psychiatry Society-2017):
•Affective Symptoms
•Need for rapid control of symptoms
•Presence of suicidal behaviour putting patientâ??s life at risk
•Presence of severe agitation or violence putting otherâ??s life at risk
•Refusal to eat, putting patientâ??s life at risk
•History of good response in the past
•Patient not responding to adequate trial of an antipsychotic medication
•Augmentation of partial response to antipsychotic medication
•Clozapine resistant schizophrenia
•Not able to tolerate antipsychotic medications
•5. Patients giving written informed consent for ECT and the study

•1. Co-morbid neurological or other psychiatric disorder (current or in past).
•2. Patient with co morbid substance dependence or abuse in last 6 months, except nicotine
•and caffeine.
•3. Subjects who have received ECT in past 6 months.
•4. Baseline score of less than 24 on Mini Mental Status Examination (MMSE

发起方

Central Institute Of Psychiatry Kanke Ranchi