Evaluation the relationship between cognitive function and inflammatory factors in patients with MS
Not Applicable
- Conditions
- Multiple Sclerosis.Multiple sclerosis
- Registration Number
- IRCT20090203001637N5
- Lead Sponsor
- Vice-Deen for Research of Faculty of Basic of Medical Science of Tarbiat Modares University (TMU)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Male and female patients by physicians specializing in neurology examination and diagnosis- relapsing remitting MS Be laid.
Age between 18 to 40 years
Having Disability 2-5 as base,Expanded Disability Status Scale ( EDSS ) .
Exclusion Criteria
participating in sports activities in a serious and regular manner at least a year before participating in the study.
Having history of cardiovascular disease and blood pressure.
Use of steroids drugs.
Use of antidepressants drugs.
Use of neuroleptics drugs.
Use of immunosuppressive drugs.
Having history of infectious illness.
Having history of metabolic illness.
Having history of i mental and cognetive illness.
Participants have no desire to continue
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Blood levels of BDNF. Timepoint: Before and after the intervention. Method of measurement: Eenzyme -linked immunosorbent assay kits.;Blood levels ofl VEGF. Timepoint: Before and after the intervention. Method of measurement: Eenzyme -linked immunosorbent assay kits.;Blood levels of IL6. Timepoint: Before and after the intervention. Method of measurement: Eenzyme -linked immunosorbent assay kits.;Blood levels of IL10. Timepoint: Before and after the intervention. Method of measurement: Eenzyme -linked immunosorbent assay kits.;Brain Cognitive function. Timepoint: Before and after the intervention. Method of measurement: Cognitive Testing Software.
- Secondary Outcome Measures
Name Time Method Quality of life. Timepoint: Before and after the intervention. Method of measurement: Questionare SF 36.