Assessment Of Carotid Flow During General Anesthesia
- Conditions
- AnesthesiaFluid Responsiveness
- Interventions
- Diagnostic Test: Fluid bolus
- Registration Number
- NCT03713008
- Lead Sponsor
- Medical University of Warsaw
- Brief Summary
Proper identification of patients who would benefit from fluid infusion (fluid responsiveness) is one of the most crucial challenges in anaesthesia and critical care. Reliability of several invasive measurements used for this purpose for many years have been questioned recently. The study will evaluate consistency between carotid artery flow derivatives and standard haemodynamic measurement (LIDCO rapid) in navigation of intraoperative fluid therapy.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 61
- Major abdominal surgery
- Artery catheter required
- Laparoscopic surgery
- Known history of carotid endarterectomy
- Known history of carotid stenosis
- Non-sinus rhythm
- Systolic or diastolic heart failure
- Chronic kidney disease
- Pulmonary hypertension
- Carotid artery anomaly
- Unable to visualise carotid artery
- Angle of correction > 60
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Fluid bolus Fluid bolus Patients included in the study will receive fluid bolus.
- Primary Outcome Measures
Name Time Method Change in cardiac output Before and 2 minutes after intervention A measure of change of scaled cardiac output (nCO) with LiDCO device
Change in a corrected carotid artery flow Before and 2 minutes after intervention Ultrasound measure of corrected carotid artery flow time
- Secondary Outcome Measures
Name Time Method Change in pulse pressure variation Before and 2 minutes after intervention A measure of change of pulse pressure variation (PPV) with LiDCO device
Change in stroke volume variation Before and 2 minutes after intervention A measure of change of pulse pressure variation with LiDCO device
Change in a carotid blood flow Before and 2 minutes after intervention Ultrasound measure of corrected carotid blood flow time
Change in the maximal systolic carotid velocity variation Before and 2 minutes after intervention Ultrasound measure of the maximal systolic carotid velocity variation
Change in a velocity time integral of carotid flow Before and 2 minutes after intervention Ultrasound measure of velocity time integral of carotid flow
Trial Locations
- Locations (1)
Medical University Of Warsaw
🇵🇱Warsaw, Mazovian, Poland