A double-blind randomized placebo controlled clinical trial evaluating the efficacy of individualized homoeopathic medicines in treatment of knee osteoarthritis

ational Institute of Homoeopathy Ministry of AYUSH Govt of India0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•1. Age 50-70 years
•2. Both sexes
•3. Diagnosed knee osteoarthritis as per American College of Rheumatology (ACR) clinical/radiographic classification criteria, (sensitivity 91%; specificity 86%):
•a) Knee pain
•b) At least 1 of 3: age more than 50 yrs, stiffness less than 30 min, and crepitus on knee motion
•c) Osteophytes on knee x-ray
•4. Patients already undergoing regular oral or topical analgesics or NSAID therapy for painful episodes of osteoarthritis, provided the medications are stopped completely at least 2 weeks prior study entry
•5. Can read Bengali
•6. Providing written informed consent

•1. Severe degeneration of knee joint with marked joint narrowing, varus, or valgus deformity of knee ( >12Â°), evidenced by imaging or other evidences and requiring surgical intervention
•2. Non-ambulant patients
•3. Self-reported joint disorders other than osteoarthritis (e.g., inflammatory joint disease, specific arthropathy, severe axis deviations or instabilities, joint or skin infections, joint prostheses of the lower limbs)
•4. Intra-articular injections within 2 weeks before study entry
•5. Transplanted knees
•6. Recent significant knee surgery within last 6 months
•7. Patients who are too sick for consultation
•8. Unwilling to take part and not giving consent to join the study
•9. Unable to read patient information sheet
•10. Diagnosed cases of unstable mental or psychiatric illness or other uncontrolled or life-threatening illness affecting quality of life
•11. Pregnancy and lactation
•12. Substance abuse and/or dependence
•13. Self-reported immune-compromised state, and
•14. Undergoing homeopathic treatment for any chronic disease within last 6 months

发起方

ational Institute of Homoeopathy Ministry of AYUSH Govt of India