CTRI/2017/08/009582
Completed
Phase 4
A randomised, double blind, comparative clinical trial assessing the effectiveness and safety of dapsone 5% versus clindamycin 1% in the treatment of mild to moderate acne vulgaris - DCRCT
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Medical College Kolkata
- Enrollment
- 51
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\.Subjects of 12 to 40 years of age of either sex
- •2\.Mild to moderate acne: \>\= 2 but \<\= 30 total lesions \- inflammatory (papules and pustules) and/or non\-inflammatory (open and closed comedones)
- •3\.Lesions in the face which correspond to a baseline investigator global assessment (IGA) score of 2 or 3
Exclusion Criteria
- •1\.Age \<12 or \>40
- •2\.Total lesion count \< 2 or \>30,
- •3\.Subjects regularly using any anti\-acne medications in the last 30 days before study entry
- •4\.Severe acne: Subjects with nodulo\-cystic lesions, acne conglobata, acne fulminans
- •5\.Pregnancy or intention of pregnancy and breastfeeding
- •6\.Patients with G6PD deficiency
- •7\.History of having taken any medication that could interact with dapsone (e.g. Trimetoprim\-sulfametoxazol
- •8\.Known hypersensitivity to the study medication
- •9\.Patients not willing to comply with protocol requirements
Outcomes
Primary Outcomes
Not specified
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