Diagnosis of intestinal metaplasia in gastric mucosa uning Blue Laser Imaging(BLI)
Not Applicable
- Conditions
- Stomach tumor-related lesion
- Registration Number
- JPRN-UMIN000026659
- Lead Sponsor
- Jichi Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Not provided
Exclusion Criteria
1) Acute abdomen 2) Severe inflammation 3) Poor general condition patients who has risk for performing endoscopy such as ileus, perforation of intestine, pancreatitis respiratory disorder, heart failure, acquired hemophilia, stricture and large ulcer or tumor of digestive tract. 4) Patients who take peroral multiple drugs including anti-platelets and anti-coagulants, leading to difficulty to take a biopsy. 5) Patients who experienced entry of this study. 6) Patiens who is judged to be unsuitable for this clinical trial. 7) Patients who are difficult to be received the informed consent.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Gastric biopsied specimens will be taken from the green change mucosa suspicious of intestinal metaplasia by BLI images, compared with white light images. Similarly, specimens will be taken from brown change mucosa suspicious of non-intestinal metaplasia. Based on the pathological findings, sensitivity, specificity and accuracy will be evaluated.
- Secondary Outcome Measures
Name Time Method Based on histological assessment of endoscopically resected specimens, the usufulness of BLI will be evaluated about the extent of tumor by color contrast between the tumor and the surrounding mucosa. In additon, the color difference will be measured using a color space International Lighting Commission recommended in 1976 in order to quantify such color contast and assess visibility of tumors by BLI.