A Comparison of The Intrathecal Isobaric Levobupivacaine With Fentanyl And Hyperbaric Levobupivacaine With Fentanyl For Proximal Femoral Nailing Surgeries: A Prospective Randomised Double Blind Controlled Study
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 72
- 试验地点
- 1
- 主要终点
- To compare the sensorial, motor block levels ,and side effects
研究概览
简要总结
In this prospective randomized controlled study , block characterstics ,side effects and hemodynamic effects will be studied between isobaric levobupivacaine and hyperbaric levobupivacaine injected intrathecally. Subarachnoid block is the most commonly used regional anesthesia technique in contemporary anesthesia practice. Motor block from subarachnoid anesthesia beyond the duration of surgery is undesirable, particularly in ambulatory setting,and this is the most important reason why subarachnoid block is not preferred in ambulatory setting.With introduction of levobupivacaine as pure S(-) enantiomer of bupivacaine which offers advantages of lower cardiotoxicity and neurotoxicity and shorter motor block duration,its use has widely increased in india.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients of ASA PS I and ASA PS II.
排除标准
- •Patient refusal Allergic to local anesthetics Pregnancy Absolute contraindications to Regional anesthesia.
结局指标
主要结局
To compare the sensorial, motor block levels ,and side effects
时间窗: Baseline | After spinal anesthesia | 3min | 6min | 9min | 12min | 15min | 20 min | 25min | 30min | 35min | 40min | 45min | At the end of surgery
次要结局
- To compare hemodynamic changes,(intraoperative analgesia requirement and time for first rescue analgesic requirement in postoperative period.)
研究者
Dr Meda Venkata Srinivas
Government Medical College,Cuddapah
