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临床试验/CTRI/2024/04/066156
CTRI/2024/04/066156尚未招募4 期

A Comparison of The Intrathecal Isobaric Levobupivacaine With Fentanyl And Hyperbaric Levobupivacaine With Fentanyl For Proximal Femoral Nailing Surgeries: A Prospective Randomised Double Blind Controlled Study

Dr Sunil Chiruvella1 个研究点 分布在 1 个国家目标入组 72 人开始时间: 2024年5月7日最近更新:
适应症
相关药物

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
72
试验地点
1
主要终点
To compare the sensorial, motor block levels ,and side effects

研究概览

简要总结

In this prospective randomized controlled study , block characterstics ,side effects  and hemodynamic effects will be studied between isobaric levobupivacaine and hyperbaric levobupivacaine injected intrathecally. Subarachnoid block is the most commonly used regional anesthesia technique in contemporary anesthesia practice. Motor block from subarachnoid anesthesia beyond the duration of surgery is undesirable, particularly in ambulatory setting,and this is the most important reason why subarachnoid block is not preferred in ambulatory setting.With introduction of levobupivacaine as pure S(-) enantiomer of bupivacaine which offers advantages of lower cardiotoxicity and neurotoxicity and shorter motor block duration,its use has widely increased in india.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant and Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • •Patients of ASA PS I and ASA PS II.

排除标准

  • •Patient refusal Allergic to local anesthetics Pregnancy Absolute contraindications to Regional anesthesia.

结局指标

主要结局

To compare the sensorial, motor block levels ,and side effects

时间窗: Baseline | After spinal anesthesia | 3min | 6min | 9min | 12min | 15min | 20 min | 25min | 30min | 35min | 40min | 45min | At the end of surgery

次要结局

  • To compare hemodynamic changes,(intraoperative analgesia requirement and time for first rescue analgesic requirement in postoperative period.)

研究者

发起方
Dr Sunil Chiruvella
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Meda Venkata Srinivas

Government Medical College,Cuddapah

研究点 (1)

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