Does DNA Sperm Fragmentation Affects Embryo Morphokinetic?
Not Applicable
Terminated
- Conditions
- Pronuclear FadingCleavage TimesPronuclear AppearanceEmbryo CompactionBlastocyst Time
- Interventions
- Other: MACS
- Registration Number
- NCT02214537
- Lead Sponsor
- IVI Madrid
- Brief Summary
The embryokinetics may be a new prognostic factor for choosing the human embryos with the highest implantation potential. In order to identify the factors that may affect the rate of embryo cleavage, there are many studies about morphokinetics and culture medium, oxygen tension, oocyte quality or type of medication used for ovarian stimulation. However there are no published data with respect to the influence of sperm DNA fragmentation in the embryo kinetic.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- Patients 36 to 38 years
- Fresh sample semen
- Minimum 6 oocytes
- Semen sample with at least 5 million/ml and at least 30% of progressive motile sperm.
Exclusion Criteria
- Patients younger than 36 or older than 38 years old
- Frozen semen sample
- Less tan 6 oocytes.
- Semen samples with less than 5 million / ml or less than 30% of motile sperm.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description MACS MACS Patients with MACS Selection
- Primary Outcome Measures
Name Time Method Time of pronuclear appearance in hours. The mean time of appearance of pronuclei is 3.3951 hours in our patients. We are going to evaluate pronuclear appearence time in hours in our study groups We want to study whether differences exist in the time of appearance of pronuclei in those embryos that derived from semen samples from the two study groups
the minimum value of the difference to be detected; we said that about 3 hours apart.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
IVI Madrid
🇪🇸Madrid, Spain