The effects of high dose of selenium in the treatment of patient with severe sepsis
- Conditions
- Severe sepsis.Systemic Inflammatory Response Syndrome of infectious origin with organ failure Severe sepsis
- Registration Number
- IRCT201212082887N4
- Lead Sponsor
- Vice chancellor for research, Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 51
Patient with suspected or documented diagnosis of infection with at least one of these: White blood cell (WBC) in sterile regions, Perforated viscera; Radiologic evidence of pneumonia and infected sputum; High risk infection such as Cholangitis; and at least three of the following: Body temperature above 38 degrees Celsius or under 36; Heart rate greater than 90 beat per minute without consuming any medication, Respiratory rate more than 20 per minute or arterial pressure of carbon dioxide less than 32 millimeter of mercury with mechanical ventilation; White blood cells more than 12000 or less than 1000; more than 10 percent band Neutrophils.
Exclusion criteria: more than 24 hours of diagnosis of sever sepsis; high probability death due to a nonspecific cause (renal insufficiency, hepatic encephalopathy, etc) within the first 28 days; pregnancy or lactating; Age less than 16 years; dissatisfaction of patient or his family to enter the study; patients with Cancer
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mortality. Timepoint: Mortality within 28 days of after diagnosis with severe sepsis. Method of measurement: Counting the number of patient died.;Length of ICU stay. Timepoint: Number of bed days in ICU since entry into the research. Method of measurement: Registration for beding in ICU.
- Secondary Outcome Measures
Name Time Method