Cypher drug-Eluting stent: a Zwolle Acute myocardial infarction Randomised trial

Not Applicable

Completed

• Conditions: Acute myocardial infarction; Circulatory System; Infarction

• Registration Number: ISRCTN90526229
• Lead Sponsor: Isala klinieken (The Netherlands)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2005-09-12
• Study Completion: 2006-12-01
• Last Update Posted: 30 August 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 352

Inclusion Criteria

1. Patients with acute myocardial infarction, presenting within six hours after symptom-onset, or those presenting between six and 24 hours if persisting chest pain associated with clinical evidence of on-going ischaemia occurs
2. Culprit lesion in a native coronary artery, suitable for stenting
3. Lesion length of less than 30 mm, located in a vessel of more than 2.5 mm
4. Able to deliver the stent to target lesion (absence of diffuse disease or excessive proximal vessel tortuosity)
5. Absence of no-reflow or extensive thrombus throughout vessel

Exclusion Criteria

1. Women of child-bearing potential
2. Severe hepatic or renal disease
3. Previous participation in the study
4. Life expectancy of less than one year
5. Factors making follow-up difficult
6. Acute myocardial infarction pre-treated with thrombolysis
7. Unprotected left main disease or single remaining vessel
8. Target lesion in a bifurcation with a large side-branch
9. Known sensitivity to aspirin or coumarin
10. Unable to provide informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified