A Study to Assess the Impact of Pneumococcal Conjugate Vaccination Programme on the Carriage of Pneumococci

Completed

• Conditions: Pneumococcal Disease

• Registration Number: NCT01040143
• Lead Sponsor: Public Health England

Brief Summary

A study taking swabs from the back of the nose (nasopharynx) to look at carriage of pneumococci.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-01
• Study First Submitted: 2009-12-28
• Study First Submitted QC: 2009-12-28
• Study First Posted: 2009-12-29
• Primary Completion: 2010-03
• Study Completion: 2010-03
• Status Verified: 2010-09
• Last Update Submitted: 2019-03-20
• Last Update Posted: 2019-03-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 450

Inclusion Criteria

• Born in a cohort eligible for routine or catch up pneumococcal conjugate vaccination (i.e. date of birth since 4th September 2004) or a family member where a child is eligible and has been enrolled
• Written informed consent given by the subject's parent/ legal guardian as well as assent from the child after the nature of the study has been explained to them or
• Written informed consent given by the subject after the nature of the study has been explained to them

Exclusion Criteria

• Moderate to severe disability.
• Cerebral palsy, syndromes and neurological disorders affecting swallowing.
• Ear Nose and Throat disorders affecting the anatomy of the ear,i.e.malformed ears.
• Confirmed or suspected immunodeficiency (congenital or acquired).
• On immunosuppressive therapy.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Presence of pneumococci in nasopharyngeal swabs

Trial Locations

Locations (1)

Health Protection Agency; 🇬🇧 London, United Kingdom