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Ventilator Hyperinflation and Manual Rib Cage Compression

Not Applicable
Completed
Conditions
Pulmonary Atelectasis
Interventions
Other: Expiratory Rib Cage Compression
Other: Compression + Ventilator Hyperinflation
Registration Number
NCT03630484
Lead Sponsor
Brazilian Institute of Higher Education of Censa
Brief Summary

This is a randomized crossover trial to evaluate the effects of thoracic compression applied alone or in association with hyperinflation maneuver with the ventilator. In addition, the mobilized volume and peak expiratory flow resulting from both maneuvers will be evaluated.

Detailed Description

Ventilator hyperinflation is widely used in hypersecretive patients. It consists of increasing alveolar ventilation by facilitating the coughing mechanism so that the secretions of the peripheral airways are mobilized into the central airways so that they can be removed by tracheal aspiration or cough. Thoracic compression consists of manually compressing the rib cage during expiration, in order to increase expiratory flow, mobilize and remove pulmonary secretions. A randomized crossover clinical trial was performed with 30 patients submitted to isolated compression or associated with ventilator hyperinflation, with a 6 hour interval. Patients were evaluated through compliance and resistance of the respiratory system.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
30
Inclusion Criteria
  • patients under mechanical ventilation
  • diagnosis of pulmonary infection
  • hypersecretive
Exclusion Criteria
  • haemodynamic instability (heart rate > 130 bpm and mean arterial pressure < 60 mmHg)
  • acute bronchospasm
  • acute respiratory distress syndrome
  • untreated pneumothorax

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
Expiratory Rib Cage CompressionExpiratory Rib Cage CompressionExpiratory rib cage compression was performed in 6 sets of 6 cycles, with 1 cycle interval. Ventilatory mode and parameters were maintained.
Compression + Ventilator HyperinflationCompression + Ventilator HyperinflationExpiratory rib cage compression was performed in 6 sets of 6 cycles, with 1 cycle interval. Ventilator hyperinflation was performed by increasing the inspiratory pressure to every 5 cmH2O until the total pressure reached 40 cmH2O, remaining the same.
Primary Outcome Measures
NameTimeMethod
Static compliance of respiratory systemBaseline (before), immediately after ventilator hyperinflation or rib cage compression and five minutes after aspiration

Compliance was assessed through the occlusion maneuver at the end of inspiration, considering tidal volume, plateau pressure and PEEP. Three measurements were taken at each moment, the mean being used.

Total Resistance of respiratory systemBaseline (before), immediately after ventilator hyperinflation or rib cage compression and five minutes after aspiration

The total resistance of the respiratory system was evaluated through the occlusion maneuver at the end of the inspiration, considering the resistive pressure, measured by the difference between the maximum plateau pressure. Three measurements were taken at each moment, the mean being used.

Airway ResistanceBaseline (before), immediately after ventilator hyperinflation or rib cage compression and five minutes after aspiration

The airway resistance was assessed by means of the occlusion maneuver at the end of the inspiration, considering the rapid fall of the pressure immediately after the occlusion, measured by the difference between the maximum pressure and P1. Three measurements were taken at each moment, the mean being used.

Peak expiratory flowBaseline (before), immediately after ventilator hyperinflation or rib cage compression and five minutes after aspiration

The peak expiratory flow was evaluated through passive expiration, being considered the greatest value of the flow in the expiratory phase.

Secondary Outcome Measures
NameTimeMethod
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