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临床试验/NCT04344171
NCT04344171Unknown不适用

CovidDB: The Covid-19 Inpatient Database

ClarData9 个研究点 分布在 2 个国家目标入组 5,000 人开始时间: 2020年3月30日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
5,000
试验地点
9
主要终点
Outcome comparison between different antiviral therapies

研究概览

简要总结

The aim of the project is to better understand the Covid-19 inpatient course of the disease and to quickly identify the positive experiences in the treatment in order to update guidelines for the treatment and use of medication.

详细描述

The exponentially increasing number of SARS-CoV-2 infected people, despite the influence of the currently existing non-medical measures, is generating a rapidly increasing number of inpatients, some of whom need artificial ventilation. The average focus is on the extent to which the hospitals' capacities will be sufficient to adequately treat all patients. Regardless of this, it can be expected that even if the non-medical measures are successful, the number of inpatients treated will remain high in the course of the pandemic. With regard to the distribution of infection, it can be expected that clinics with a wide range of expertise will have to treat a large number of Covid-19 patients.

So far, however, there is little to no experience in treating patients. In addition to epidemiological data, only case descriptions and some Chinese studies mostly from Wuhan based on fewer patients are available. In view of the rapidly spreading pandemic, preprints are increasingly being used. What has been missing so far is a uniform, structured recording of the courses of Covid-19 inpatients handled by many clinics, which goes beyond the epidemiological events in terms of depth of detail. With this documentation of real processes, the basis for a large number of studies and the associated better understanding of the disease process could be created.

The current dynamics make it imperative that the clinics, even those who have not received the most up-to-date scientific knowledge, cannot wait for the results of studies, but rather need concrete help in the treatment of patients. Efficient assistance within the framework of a close exchange between the treatment units is only possible with a multicentre, uniform documentation environment.

The aim of the project is to better understand the Covid-19 inpatient course of the disease and to quickly identify the positive experiences in the treatment in order to update guidelines for the treatment and use of medication.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

性别
All
接受健康志愿者

入选标准

  • Covid-19 inpatients

排除标准

  • assumed Covid-19 patient

结局指标

主要结局

Outcome comparison between different antiviral therapies

时间窗: through study completion, an average of 1 year

Different antivirals and their combinations will be tested and the outcome (cured/deceased) will be assessed

Outcome comparisons between ventilation types

时间窗: through study completion, an average of 1 year

Different ventilation types will be tested and the outcome (cured/deceased) will be assessed

Identification of risk factors

时间窗: through study completion, an average of 1 year

Clinical and laboratory risk factors will be recorded and the outcome (cured/deceased) will be assessed

Number of days in hospital vs. clinical classification

时间窗: through study completion, an average of 1 year

Correlation between number of days in hospital and worst clinical classification will be calculated

次要结局

未报告次要终点

研究者

发起方
ClarData
申办方类型
Other
责任方
Sponsor

研究点 (9)

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CovidDB: The Covid-19 Inpatient Database | 临床试验