Optimizing Mindfulness and Acceptance Based Behavioral Treatment for Bulimia Nervosa and Binge Eating Disorder

Not Applicable

Active, not recruiting

Conditions: Bulimia Nervosa
Bulimia; Atypical
Binge Eating
Binge-Eating Disorder
Binge-Eating and Purging Type Anorexia Nervosa

Brief Summary: The current study will use a full factorial design to identify the independent and combined effects of four core MABT components when combined with standard behavioral treatment for BN and BED. The primary aim of the study will be to evaluate the independent efficacy of Mindful Awareness, Distress Tolerance, Emotion Modulation, and Values-Based Decision Making on eating pathology (at posttreatment and at 6 and 12-month follow-ups). Secondary aims will be (1) to test target engagement of each MABT component, i.e., to confirm that each treatment component impacts both the variable which it targets and self-regulation and that improvements in these are associated with improvements in outcomes and (2) to test the hypotheses that the efficacy of each component is moderated by related baseline deficits in self-regulation (e.g. individuals with worse distress tolerance at baseline are most likely to benefit from conditions that include the Distress Tolerance component). A final exploratory aim will be to quantify the component interaction effects, which may be partially additive (because components overlap and/or there is diminishing return), fully additive, or synergistic (in that components may partially depend on each other).

Recruitment & Eligibility

Inclusion Criteria

Have experienced 12 or more loss of control episodes within the previous 3 months
Have a BMI above 16
Are located in the US and wiling/able to participate in remote treatment and assessments
Are able to give consent

Exclusion Criteria

Are unable to fluently speak, write and read English
Have a BMI below 16
Are receiving treatment for an eating disorder
Require immediate treatment for medical complications as a result of eating disorder symptoms
Have a mental handicap, or are experiencing other severe psychopathology that would limit the participants' ability to comply with the demands of the current study (e.g. severe depression with suicidal intent, active psychotic disorder)

Arm && Interventions

Group	Intervention	Description
Base BT	Behavioral Therapy for Eating Disorders	16 weekly sessions of behavioral therapy.

Primary Outcome Measures

Name	Time	Method
Binge eating frequency assessed by the Eating Disorder Examination	Changes from each assessment time point throughout treatment (3 assessments over 16 weeks) and 6-month and 1 year post-treatment follow-up assessment	Frequency (number of days and number of instances) of binge eating over the past 28 days assessed by the Eating Disorder Examination
Eating Disorder Examination	Changes from each assessment time point throughout treatment (3 assessments over 16 weeks) and 6 month and 1 year post-treatment follow-up assessment	The Eating Disorder Examination is a semi-structured interview that measures eating pathology. The EDE yields four subscale scores: Restraint, Eating Concern, Shape Concern, and Weight Concern. The possible score range for each subscale is 0 to 6. The total score may also be reported (determined by averaging the subscale scores); the score range for the total score is also 0 to 6. For subscale scores and total score, higher scores indicate more severe pathology. The restraint sub-scale of the EDE will be used to assess utilization of skills related to reducing dietary restraint.
Remission Status	Changes from each assessment time point throughout treatment (3 assessments over 16 weeks) and 6 month and 1 year post-treatment follow-up assessment	Presence or absence of eating disorder diagnosis. Not in remission; in partial remission; or in full remission.

Secondary Outcome Measures

Name	Time	Method
Compensatory behavior frequency assessed by the Eating Disorder Examination (EDE)	Changes from each assessment time point throughout treatment (3 assessments over 16 weeks) and 6 month and 1 year post-treatment follow-up assessment	Frequency (number of days and number of instances) of compensatory behaviors assessed by the Eating Disorder Examination
BMI	Changes from each assessment time point throughout treatment (3 assessments over 16 weeks) and 6 month and 1 year post-treatment follow-up assessment	kilogram/(meters\^2), this is an outcome measure for participants with anorexia nervosa, binge/purge type

Locations (1): Drexel University, Stratton Hall
🇺🇸
Philadelphia, Pennsylvania, United States