Total versus near-total thyroidectomy in Graves`disease- a multi centered prospective randomized controlled clinical trial to evaluate postoperative transient hypoparathyroidism after definite surgery in Graves`disease
Not Applicable
Recruiting
- Conditions
- E89.2E05.0Postprocedural hypoparathyroidismThyrotoxicosis with diffuse goitre
- Registration Number
- DRKS00004161
- Lead Sponsor
- Klinik für Viszeral-, Thorax- und GefäßchirurgieUniversitätsklinikum Gießen und Marburg GmbH- Standort Marburg
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
Patients with Graves` disease indicated for definite surgery according to the national guideline; indications are: intolerance of thermostatic medication, persistent or recurrent hyperthyreosis, thyroid growth, endocrine orbitopathy, contraindications for radio iodine therapy; other inclusion criteria are: no history of previous thyroid- and/ or parathyroid surgery; Normal vocal cord function; Age >/= 18 years; Expectancy of life greater than 12 months; Informed consent
Exclusion Criteria
Patients with Graves` disease eligible for conservative treatment; (Suspected) malignancy; impairment of parathyroid function; Neurophysiological deficiencies
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method