Controlled decompression effects in the patients with severe TBI: A Randomized Control Trial

Not Applicable

• Conditions: Traumatic brain injury.; Diffuse traumatic brain injury; S06.2

• Registration Number: IRCT20230907059376N1
• Lead Sponsor: Afridi Medical Complex, Peshawar

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 16 October 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

Patients with TBI between the ages of 18 and 75
Patients who gave informed permission
Glasgow Coma Scale (GCS) score between 3 and 8 at admission

Exclusion Criteria

Initial need for bilateral craniotomy
Preoperative GCS score of 3 with no improvement after treatment in the emergency room
Presentation without attenuated respiration and blood pressure
Combination of anoxia and hypotension with brain swelling caused by anoxia or hypotension and minor intracranial bleeding after injury
Coagulation disorder or a history of aspirin intake and multiorgan malfunction

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Global disability and recovery after traumatic brain injury. Timepoint: Baseline and after 6 months. Method of measurement: Extended Glasgow Outcome Scale (GOSE).