europrotective efficacy of topical unoprostone isopropyl or nipradilol in patients with retinitis pigmentosa

Not Applicable

• Conditions: retinitis pigmentosa

• Registration Number: JPRN-UMIN000006820
• Lead Sponsor: Kyushu university hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-12-02
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Not provided

Exclusion Criteria

(1) a past history of glaucoma or ocular hypertension (2) patients with another macular disorder, such as epiretinal membrane (3) a past history of using the test drug within 6 months (4) pregnant subjects, subjects suspected of being pregnant, or breast-feeding subjects (5) hypersensitivity to the test drug (6) a past history of the entry into another clinical trial within 1 year (7) inappropriate case judged by investigator or subinvestigators

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The efficacy of the treatment was monitored by the following parameters before and after treatment (6 months or 12 months). (1) best corrected visual acuity (2) visual field measurement testing using the Humphrey Field Analyzer (HFA: the central 10-2 Program) (3) retinal sensitivity measurement using microperimeter (MP-1) (4) retinal circulation measurement using Laser Speckle flowgrafy