Wavefront-guided LASIK for Correction of Myopia
- Conditions
- Myopia
- Registration Number
- NCT01682434
- Lead Sponsor
- Aarhus University Hospital
- Brief Summary
Laser in situ keratomileusis is a successful procedure for the treatment of low to moderate myopia.
Advances over the last decade have allowed LASIK to also correct higher order wavefront aberrations. In low myopia, there seem to be a minor effect of such wavefront-guided treatment. However, it remains to be established whether there is a beneficial effect in higher degrees of myopia.
The study aims to determine whether myopic subjects (-6 to -10 diopters) with higher-than-average preoperative higher-order aberrations have benefit of wavefront-guided treatment. Subjects are randomized to wavefront-guided treatment in one eye, and conventional treatment in the other.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
- Age 20 to 50 years
- No known ocular or systemic disease
- Not pregnant or breastfeeding
- Myopia between -6.0 and -10.0 diopters
- Astigmatism below 2.0 diopters
- Difference of less than 1.0 diopters in spherical equivalent between eyes
- Normal corneal topography
- Corneal thickness sufficient for planned treatment
- Patients that do not fulfill inclusion criteria
- Insufficient quality of ocular wavefront measurement
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Visual acuity 12 months
- Secondary Outcome Measures
Name Time Method Ocular higher order aberrations 12 months Hartmann-Schack wavefront aberrometry using the Zeiss Meditec WASCA
Trial Locations
- Locations (1)
Department of Ophthalmology, Aarhus University Hospital
🇩🇰Aarhus, Denmark
Department of Ophthalmology, Aarhus University Hospital🇩🇰Aarhus, Denmark