Evaluation of the Feasibility and Impact of Introducing Malaria Rapid Diagnostic Tests in the Retail Sector: A Randomized Controlled Trial in Eastern Uganda
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 2,800
- 试验地点
- 2
- 主要终点
- Fraction of Illnesses Diagnosed for Malaria
研究概览
简要总结
The purpose of this study is to assess the feasibility and impact of introducing subsidized malaria rapid diagnostic tests (RDTs) into retail sector drug shops in Uganda. This is a randomized controlled trial at the village level, taking place in 6 districts in Eastern Uganda. Licensed drug shops in selected villages were trained in proper RDT storage, administration, interpretation and disposal and were given access to subsidized RDTs for sale. This study explores whether drug shop owners--when given access to training and subsidized RDTs--will choose to promote and sell RDTs to customers and, if so, at what volume and what price. The investigators also explore whether shops will safely store, administer, interpret and dispose of RDTs and to what extent they will use RDT results to guide treatment recommendations. Finally, the study explores whether making RDTs available for sale in local drug shops has a community level impact on diagnostic testing and appropriate treatment for malaria.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Drug Shops:
- •Licensed and registered as a Drug Shop with the Ugandan National Drug Authority
- •Households:
- •Live in the village of participating drug shop
- •Female household head is 18 or over
排除标准
- •Drug Shops:
- •Drug Shop not registered with Ugandan National Drug Authority
- •Female household head is under 18
结局指标
主要结局
Fraction of Illnesses Diagnosed for Malaria
时间窗: Up To One Year
Comparison of the rate of malaria diagnosis in treatment vs. control. Comparison will be at the village level and at the shop level. Denominator will be: all illnesses, febrile illnesses only or suspected malaria episodes only.
次要结局
- Mean RDT Price Charged by Shops(Up to One Year)
- Mean RDTs Purchased by Shops from Wholesaler(Up To One Year)
- Fraction of Monitoring Checklist Items Performed Correctly by Shops(Up To One Year)
- Fraction of Illnesses for which an Antimalarial/ACT/Antibiotic is Taken(Up To One Year)
研究者
Jessica Cohen
Assistant Professor
Harvard School of Public Health (HSPH)
