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Effect of infusion of B-type Natriuretic Peptide in Acute Exacerbation of Asthma

Phase 1
Conditions
Acute Exacerbation of Asthma.
Asthma
Registration Number
IRCT2015022215446N2
Lead Sponsor
Vice challencor for reasearch of Ahvaz Jundishapur University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
40
Inclusion Criteria

Inclusion Criteria: Acute Asthma Attack with: Age above 18 years old; Clinically or Para-clinically Asthma History

Exclusion Criteria

History of Cardiovascular Diseases; History of COPD; History of other pulmonary diseases; History of Smoking more than 10 years; Pregnant women; History of hypersensitivity to the BNP; Systolic Blood Pressure less than 100 mmHg

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Forced Expiratory Volume in First Second (FEV1). Timepoint: Before intervention, 30 minutes after intervention, 60 minutes after intervention, 90 minutes after intervention. Method of measurement: Milliliter with use of Peak Flow Meter.;Peak Expiratory Flow Rate (PEFR). Timepoint: Before intervention, 30 minutes after intervention, 60 minutes after intervention, 90 minutes after intervention. Method of measurement: Milliliter with use of Peak Flow Meter.
Secondary Outcome Measures
NameTimeMethod
Blood Pressure. Timepoint: Before Intervention. Method of measurement: Millimeter of Hg.
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