Efficacy of Ketamine on Acute Pai
Phase 3
Recruiting
- Conditions
- Acute pain.Acute pain, not elsewhere classifiedG89.1
- Registration Number
- IRCT20200608047684N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
Any adult patient (age>18) with acute pain who need analgesia
Exclusion Criteria
Pain score =5
Pregnancy and post-partum women
Altered mental status
Allergy to ketamine or fentanyl
Body weight = 46 kg or = 115
Unstable vital signs: BP= 90 mmHg or = 180 mmHg , PR=150 or =50 bits/min , RR=10 or =30
History of recent head or eye trauma
History of Siesure
History of elevated ICP
Chronic pain
Renal or hepatic failure
Substance or alcohol abuse
Documented psychiatric disorders
Opium addiction
Recent use of narcotic analgesics
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain score by Verbal Numerical Rating Scale (VNRS). Timepoint: 5,10,15 and 30 minutes after administration of medications. Method of measurement: Verbal Numerical Rating Scale (VNRS).;Blood pressure. Timepoint: 5,10,15 and 30 minutes after administration of medications. Method of measurement: Sphygmomanometer.
- Secondary Outcome Measures
Name Time Method Agitation scale calculating with Richmond Agitation-Sedation Scale. Timepoint: When agitation appears. Method of measurement: Richmond Agitation-Sedation Scale.;Need for rescue analgesic. Timepoint: 10 minutes after administration of medications. Method of measurement: Asking from patient about presence of pain.