Effect of exercise training on sarcopenia in elderlies
Not Applicable
- Conditions
- With aging, there is an inevitable progressive loss of muscle mass and strength called sarcopenia that is associated with the risk of impairment in physical ability which could lead to consequences such as falls, fall-related injuries, hospitalizations, and even mortality..Muscle wasting and atrophy, not elsewhere classifiedM62.5
- Registration Number
- IRCT20230727058944N1
- Lead Sponsor
- Allameh Tabataba'i University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Male
- Target Recruitment
- 30
Inclusion Criteria
Age more than 65 years
Handgrip strength lower than 32Kg
SMM/height2 lower than 9.2 kg/m2
Being sedentary for at least 1 year (didn’t have more than 1h exercise per week)
Exclusion Criteria
Cardiovascular or pulmonary diseases, diabetes, Joint and muscle problems, and Mental and cognitive disorders
Involvement in any extra exercise training programs
Not interested to continue or change in personal life schedule
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Myostatin levels. Timepoint: 24 hours before intervention and 48 hours after intervention. Method of measurement: Collection of venous blood samples with a syringe and laboratory assessments.;Follistatin levels. Timepoint: 24 hours before intervention and 48 hours after intervention. Method of measurement: Collection of venous blood samples with a syringe and laboratory assessments.;GDF-15 levels. Timepoint: 24 hours before intervention and 48 hours after intervention. Method of measurement: Collection of venous blood samples with a syringe and laboratory assessments.;CAF levels. Timepoint: 24 hours before intervention and 48 hours after intervention. Method of measurement: Collection of venous blood samples with a syringe and laboratory assessments.
- Secondary Outcome Measures
Name Time Method Handgrip strength. Timepoint: 24 hours before intervention and 48 hours after intervention. Method of measurement: Jamar hand dynamometer (USA) with five handle positions and the second position was used for all participants.;Gait speed. Timepoint: 24 hours before intervention and 48 hours after intervention. Method of measurement: Walking speed of participants was assessed using a stopwatch.;Time Up and Go (TUG). Timepoint: 24 hours before intervention and 48 hours after intervention. Method of measurement: TUG test was assessed using a stopwatch.;Chair stand speed. Timepoint: 24 hours before intervention and 48 hours after intervention. Method of measurement: chair stand test was assessed using a stopwatch.;Standing balance. Timepoint: 24 hours before intervention and 48 hours after intervention. Method of measurement: The standing balance test was assessed using a stopwatch.