Promoting Adherence to Treatment in Schizophrenia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 174
- 试验地点
- 2
- 主要终点
- Number of Participants who are Hospitalized in a Psychiatric Inpatient Unit
研究概览
简要总结
The project evaluates a culturally adapted, family-based intervention designed to promote treatment adherence among Mexican-Americans with schizophrenia using a randomized, controlled design in a public mental health setting. Mexican-American patients with schizophrenia and their families were randomly assigned to either: 1) one year of multi- family groups that emphasize the importance of attitudes towards adherence, subjective norms, and self-perceived and actual adherence skills in maintaining adherence, added to ongoing customary outpatient care; 2) standard multi-family groups without an emphasis on medication adherence, added to customary outpatient care; or 3) customary outpatient care only (monthly pharmacotherapy sessions and additional services as clinically needed). The study hypotheses are that subjects assigned to the adapted multi-family group would have better medication adherence, less psychiatric symptoms and fewer psychiatric hospitalizations throughout the course of the study (one year of treatment and one year of follow up) compared to the comparison conditions.
详细描述
As above
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •DSM-IV diagnosis of schizophrenia or schizoaffective disorder;
- •Between 18 and 50 years of age;
- •Of Mexican origin and speaks Spanish fluently;
- •Was without antipsychotic medication without medical authorization for one continuous week in the month prior to hospitalization;
- •Was living with his/her family of origin immediately preceding the inpatient stay and would return to live with his/her family after discharge; and
- •The patient and at least one family member were willing to participate.
排除标准
- •Patient on conservatorship or legal guardian status
结局指标
主要结局
Number of Participants who are Hospitalized in a Psychiatric Inpatient Unit
时间窗: two years
Psychiatric hospitalization will be monitored through the use of the Los Angeles County Department of Mental Health Management Information System. This allows for the data capture of all participants who are hospitalized in an inpatient unit anywhere in Los Angeles County throughout the two-yaer course of the study. Although the primary outcome variable is whether or not a participant has been hospitalized within a given assessment period, the number of hospitalizations and the number of days hospitalized across all assessment periods will be assessed, as well.
次要结局
- Number of participants who are at least 80% adherent to their antipsychotic medication regimens during a particular assessment period(two years)