Ridge Augmentation With Simultaneous Implant Placement Using Bone Blocks With Autogenous Tooth Graft

Not Applicable

Completed

• Conditions: Ridge Augmentation; Implant; Autogenous Tooth Graft
• Interventions: Procedure: ABB and ABG with simultaneous implant placement; Procedure: ABB and ATG with simultaneous implant placement; Procedure: XBB and ATG with simultaneous implant placement

• Registration Number: NCT05407363
• Lead Sponsor: Kafrelsheikh University

Brief Summary

Autogenous bone, with its osteogenic, osteoinductive, and osteo-conductive characteristics has been used for bone grafts with optimal integration into host tissues. For this reason, autogenous bone has been often considered the gold standard of bone regeneration material. However, the amount of autogenous bone that may be harvested is limited, and the harvesting procedure is traumatic.

Bone substitutes, including allografts, xenografts, and alloplasts have been used successfully as alternatives to autogenous bone grafts in ridge augmentation procedures.

In 2008, autogenous tooth bone graft (ATG) was introduced and used for the first time as a bone grafting material for GBR. The tooth contents are extremely similar to that of the alveolar bone. The enamel inorganic, organic, and water contents are 95 percent, 0.6 percent, and 4 percent, respectively. However, in the dentin, the percentages are 70 to 75 percent, 20 percent, and 10 percent, respectively. They are 65 percent, 25 percent, and 10 percent, respectively, when compared to the alveolar bone content.

The aim of this study is to compare ridge augmentation using autogenous bone block (ABB) with immediate implant placement and filling the generated gap with autogenous bone graft (ABG) or ATG, or ridge augmentation using xenograft bone block (XBB) with immediate implant placement and filling the generated gap with ATG.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-04-01
• Study First Submitted: 2022-04-01
• Study First Submitted QC: 2022-06-02
• Study First Posted: 2022-06-07
• Primary Completion: 2023-08-12
• Study Completion: 2023-08-20
• Status Verified: 2023-12
• Last Update Submitted: 2023-12-19
• Last Update Posted: 2023-12-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Teeth with buccal bone destruction by periodontal disease and need extraction (horizontal or vertical bone defect);
• Absence of acute inflammation;
• Absence of uncontrolled systemic illness that would preclude implantation;
• Good dental and systemic healthy conditions;
• Patients were willing and able to return for multiple follow-up visits.

Exclusion Criteria

• Patients with systemic illnesses,
• psychological abnormalities,
• para-functional habit,
• smokers or alcoholics,
• pregnant and lactating patients,
• patients undergoing or recently completed radiotherapy or chemotherapy,
• patients on drugs affecting the healing process,
• patients with endodontically treated teeth

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
ABB and ABG with immediate implant	ABB and ABG with simultaneous implant placement	Using ABB with ABG to fill the gap around immediately placed dental implants
ABB and ATG with simultaneous implant placement	ABB and ATG with simultaneous implant placement	Using ABB with ATG to fill the gap around simultaneously placed dental implants
XBB and ATG with simultaneous implant placement	XBB and ATG with simultaneous implant placement	Using XBB with ATG to fill the gap around simultaneously placed dental implants

Primary Outcome Measures

Name	Time	Method
Clinical evaluation probing pocket depth and amount of bone around simultaneously placed dental implants	9 months	Changes on pocket depth and amount of bone using ABG or ATG with ABB or XBB around simultaneously placed dental implants
radiographic outcome measuring the amount of bone around simultaneously placed dental implants	9 months	the radiographic outcome by measuring the amount of bone by using ATG or ABG on bone formation with ABB or XBB around simultaneously placed dental implants

Trial Locations

Locations (1)

Faculty of Dentistry, Kafrelsheikh University; 🇪🇬 Kafr Ash Shaykh, Egypt