NL-OMON41695已完成不适用
Paracetamol or NSAID's in acute musculoskeletal syndromes - The PanAm Study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 547
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- adult patients aged * 18 years
- •- non-penetrating limb injury, meaning a painful, acute strain, sprain or contusion of an extremity
- •- trauma occurred within 48 hours before presentation
排除标准
- •- previous treatment with analgesia for the same injury
- •- self inflicted injury (*auto-mutilation*)
- •- presence of wound, joint dislocation, fracture or more then one injury
- •- daily use of paracetamol and/or NSAID*s and/or other analgesia within two weeks before presentation
- •- patients with chronic pain
- •- previous adverse reaction or known allergy to paracetamol, NSAID*s or omeprazol
- •- pregnancy
- •- previous gastro-intestinal hemorrhage or perforation after NSAID use
- •- active or recurrent peptic ulceration or peptic bleeding (2 or more evident episodes)
- •- previous exacerbation of asthma after use of NSAID*s or acetylsalicylic acid
- •- severe cardiac failure
- •- liver cirrhosis
- •- severe renal insufficiency (eGFR<30mL/min)
- •- bone marrow depression or blood dyscrasia (active or in past medical history)
- •- combined use of angiotensin converting enzyme inhibitors (or angiotensin receptor blockers) AND diuretics
- •- physical, visual or cognitive impairment or non-Dutch language speaking (unable to use NRS, pain diary or EQ5D questionnaire)
研究者
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