Efficacy of a Unani pharmacopeial formulation in Waram Majra-i-Bawl in women: A randomized standard controlled study

In Unani medicine*,Waram Majra-i-Bawl (urinary tract infection)describedas an infection that starts in the urinary system which includes Waramal-Kulya, Waram al-Mathana  and Waramal-Ahlil1which may be considered as similar with clinical findings of urinarytract infection (UTI), described in conventionalmedicine.Antibiotics are themain stay treatment for acute and recurrent UTI.  However, antibiotic resistance is estimated20% for trimethoprim and cephlosporins and 50% for amoxicillin.Further,it is predicted that antibiotic resistance will continue to increase. Sometimesside effects may require treatment to be withdrawn. Once prophylaxis isdiscontinued even after extended periods of therapy 50% to 60% of women becomere infected with in three months.Therefore, the need for alternativetherapies for UTI is evident. For centuries plants have been used throughoutthe world as drugs and remedies for various diseases.Unaniclassical texts and pharmacopeia are enriched with medicines useful in Waram Majra-i-Bawl.* Below mentioned compound formulation of Unani pharmacopeia is usefulin Waram Majra-i-Bawl, contains Tukhme Khayarein,Tukhme Kaddu, Khurfa, Tukhme Khubbazi, and Parsiaavashaan. These plant products possesses Muhallilal-Waram, Musakkin-i-Alam, Mudirr-i-Bawl, and D**afi‘-i-‘Ufunat properties.Pharmacologically they are proven for antimicrobial and anti-inflammatoryproperties.  This is a pilot study on ten patients as advised by the ethical committee.