Effect of a Unani treatment in urinary infection.

Completed

• Conditions: Urinary tract infection, site notspecified,

• Registration Number: CTRI/2020/02/023404
• Lead Sponsor: National Institute of Unani Mediicne

Brief Summary

In Unani medicine*,**Waram* *Majra-i-Bawl* (urinary tract infection)describedas an infection that starts in the urinary system which includes *Waramal-Kulya,* *Waram* *al-Mathana*  and *Waramal-Ahlil1*which may be considered as similar with clinical findings of urinarytract infection (UTI), described in conventionalmedicine.Antibiotics are themain stay treatment for acute and recurrent UTI.  However, antibiotic resistance is estimated20% for trimethoprim and cephlosporins and 50% for amoxicillin.Further,it is predicted that antibiotic resistance will continue to increase. Sometimesside effects may require treatment to be withdrawn. Once prophylaxis isdiscontinued even after extended periods of therapy 50% to 60% of women becomere infected with in three months.Therefore, the need for alternativetherapies for UTI is evident. For centuries plants have been used throughoutthe world as drugs and remedies for various diseases.Unaniclassical texts and pharmacopeia are enriched with medicines useful in *Waram* *Majra-i-Ba*w*l.* Below mentioned compound formulation of Unani pharmacopeia is usefulin *Waram* *Majra-i-Ba*w*l*, contains *Tukhme Khayarein*,*Tukhme Kaddu, Khurfa, Tukhme* *Khubbazi,* and *Parsiaavashaan*. These plant products possesses *Muhallilal-Waram*, *Musakkin-i-Alam, Mudirr-i-Bawl*, and *D**afi‘-i-‘Ufunat* properties.Pharmacologically they are proven for antimicrobial and anti-inflammatoryproperties.  This is a pilot study on ten patients as advised by the ethical committee.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-02-20
• Last Update Posted: 2024-02-20

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 10

Inclusion Criteria

• Women diagnosed with clinical features such as Pusht me Dard, Usr al-bawl(dysuria), Bawl al-Dam(haematuria), Salsal al-Bawl(urgency), Hurqa al-Bawl(Burning), Taqtir al-Bawl (dribbling).
• Clinical features of uncomplicated urinary tract infection (uUTI) symptom as per UTI Assessment (UTISA) questionnaire.

Exclusion Criteria

• Women aged up to 18 years and over 60 years.
• Pregnant and lactating women Those with complicated UTI such as associated with pyelonephritis, urolithiasis, diabetes, neurological conditions or urinary tract obstructions.
• Women who will be catheterised.
• Hypersensitivity to nitrofurantoin and impaired renal function.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in clinical features (urinary frequency, urgency, dysuria or haematuria) assessed by UTISA questionnaire	after trial on 9th or 10th day

Secondary Outcome Measures

Name	Time	Method
Reduction in Severity (e.g., intensity of pain, urgency, frequency and burning) of uncomplicated UTI.6	2. Improvements in quality of life (as estimated by validated outcomes measures SF-12).

Trial Locations

Locations (1)

National Institute of Unani Medicine Hospital; 🇮🇳 Bangalore, KARNATAKA, India

National Institute of Unani Medicine Hospital

🇮🇳Bangalore, KARNATAKA, India

Dr Arshiya Sultana

Principal investigator

9740915911

drarshiya@yahoo.com