Effect of APC and Epo on the Inflammatory Response During Sepsis

Completed

• Conditions: Systemic Inflammation; Sepsis

• Registration Number: NCT00229034
• Lead Sponsor: Lawson Health Research Institute

Brief Summary

An observational study to determine the effect of APC and Epo in reducing the systemic inflammatory response during severe sepsis.

Detailed Description

An observational study to determine the effect of APC and Epo in reducing the systemic inflammatory response during severe sepsis. Patients already prescribed either drug will be enrolled. The microcirculation of the sublingual vascular bed will be observed with a microscope to detect the alterations in the inflammatory response.

Study Timeline

• Study Start: 2005-09
• Study First Submitted: 2005-09-27
• Study First Submitted QC: 2005-09-27
• Study First Posted: 2005-09-29
• Primary Completion: 2010-12
• Study Completion: 2011-09
• Status Verified: 2017-08
• Last Update Submitted: 2017-08-24
• Last Update Posted: 2017-08-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• patients in the ICU in severe septic shock undergoing APC and/or Epo treatment

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Exclusion Criteria

• any severe comorbid conditions

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Lawson Health Research Institute; 🇨🇦 London, Ontario, Canada