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Clinical Trials/NCT07264946
NCT07264946
Completed
Not Applicable

The Effect of Talocrural Joint Manipulation on Ankle Muscle Architecture: A Randomized Crossover Trial

Bitlis Eren University1 site in 1 country36 target enrollmentStarted: October 10, 2025Last updated:

Overview

Phase
Not Applicable
Status
Completed
Sponsor
Bitlis Eren University
Enrollment
36
Locations
1
Primary Endpoint
Ankle Muscle Architecture

Overview

Brief Summary

The aim of this study is to investigate the effect of talocrural joint manipulation on the ankle muscle architecture in patients with stroke.

Detailed Description

The study, utilizing a randomized crossover design, is planned to be conducted on a minimum of 26 patients with stroke who meet the inclusion and exclusion criteria. Patients included in the study will be randomly assigned to receive both placebo talocrural joint manipulation and talocrural joint manipulation interventions.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Crossover
Primary Purpose
Treatment
Masking
Double (Participant, Outcomes Assessor)

Masking Description

The evaluator and the researcher administering the intervention will be different. The interventions will be administered to participants randomly.

Eligibility Criteria

Ages
45 Years to 75 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Six months or longer elapsed since the stroke,
  • A Mini-Mental State Examination score of 24 or higher,
  • Being between 45 and 75 years of age,
  • Having a Brunnstrom stage of 4 or above

Exclusion Criteria

  • The presence of severe osteoarthritis in the lower extremity,
  • The presence of cancer or diabetic neuropathy,
  • The presence of vestibular disorder,
  • The presence of lower extremity ulceration or amputation,
  • Hemodynamic instability,
  • The presence of other neurological disorders (such as multiple sclerosis, Parkinson's disease),
  • Having experienced an acute lower extremity injury in the last six weeks,
  • History of lower extremity surgery

Outcomes

Primary Outcomes

Ankle Muscle Architecture

Time Frame: Change from baseline ankle muscle architecture immediately after the intervention

The effect of talocrural joint manipulation on ankle muscle architecture will be evaluated using ultrasound imaging. The device will be used to analyze the pennation angle of the medial and lateral gastrocnemius muscles as well as the tibialis anterior muscle.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Bitlis Eren University
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Omer Dursun

Asst. Prof.

Bitlis Eren University

Study Sites (1)

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