Effect of Inspiratory Muscle Training During PR on Dyspnoea and Exercise Tolerance in COPD Patients

Not Applicable

Completed

• Conditions: Chronic Obstructive Pulmonary Disease
• Interventions: Other: Pulmonary rehabilitation+IMT; Other: Pulmonary rehabilitation

• Registration Number: NCT04120142
• Lead Sponsor: Faculty of Medicine, Sousse

Brief Summary

Chronic obstructive pulmonary disease is a respiratory disease that results in progressive airflow limitation and respiratory distress.

The benefit of inspiratory muscle training (IMT) combined with a pulmonary rehabilitation programme is uncertain. The investigators aimed to demonstrate that, in patients with obstructive pulmonary disease, IMT performed during a PRP is associated with an improvement of dyspnoea and exercise tolerance.

Detailed Description

The purpose of this study is to evaluate the effect of the inspiratory muscle training (with incremental load every two weeks in two months) performed during pulmonary rehabilitation on dyspnoea, 6 minutes walk test and quality of life using the St George's respiratory questionnaire (SGRQ) in COPD patients.

Study Timeline

• Study Start: 2019-02-01
• Study First Submitted: 2019-09-30
• Study First Submitted QC: 2019-10-06
• Study First Posted: 2019-10-09
• Primary Completion: 2019-12-01
• Study Completion: 2019-12-01
• Status Verified: 2020-01
• Last Update Submitted: 2020-01-31
• Last Update Posted: 2020-02-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 34

Inclusion Criteria

• Were COPD diagnosed by pulmonary function testing
• Clinically stable
• Abscence of other obstructive diseases
• Signed written consert

Exclusion Criteria

• Were previous pneumonectomy or lobectomy in the past 6 months
• spontaneous risk of pneumothorax or rib fracture
• Incapacity to follow a standard rehabilitation programme (locomotor deficits, acute cardiac failure and acute exacerbation of COPD at the beginning of the programme)
• The absence of written informed consent.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
IMT goup	Pulmonary rehabilitation+IMT	Inspiratory muscle training + aerobic exercice
Control group	Pulmonary rehabilitation	aerobic exercice

Primary Outcome Measures

Name	Time	Method
Inspiratory muscle strength	Baseline, After 2 months	The inspiratory muscle strength were measured by maximal inspiratory pressure test
Dyspnoea	Baseline, After 2 months	The dyspnoea were measured before and after the 6 minutes walk test

Trial Locations

Locations (1)

Bilel TOUNSI; 🇹🇳 Sousse, Tunisia