Application of EULAR Recommendations for Cardiovascular Risk Management in Patients With Rheumatoid Arthritis

• Conditions: Cardiovascular Check-up in Patients With Rheumatoid Arthritis
• Interventions: Other: Cardiovascular check-up

• Registration Number: NCT01566851
• Lead Sponsor: Centre Hospitalier Universitaire de Nice

Brief Summary

Introduction Cardiovascular diseases are the first cause of death in rheumatoid arthritis (RA). In 2010, EULAR Standing Committee for Clinical Affairs provides 10 recommendations for cardiovascular risk management in patients with rheumatoid arthritis, including a cardiovascular risk assessment annually.

The goal of this study is to evaluate the application of EULAR recommendations in real life in patients with RA in the french population. Inclusion criteria: all patients over 18 years old with rheumatoid arthritis treated with at least one DMARDS and/or biologic therapy, affiliated to the RSI (regime social des independents which correspond to other branches of the universal healthcare insurance agency). Non inclusion criteria: patients declared as rheumatoid arthritis without DMARDS or biologic therapy or treated with steroids alone. The following analysis will be performed on the whole database of the RSI, without name identification. Evaluation criteria: at least once a years the prescription of at least one of the following items use in the evaluation of the cardiovascular risk factors: lipides dosage, glycemia, HbA1C, stress test, Carotid ultra-sonography, coronary or lower limbs arteriography, heart ultra-sonography, cardiology clinic, endocrinology clinic. This evaluation will be done on the whole national population of RSI for the year 2011 (01/01/2011 - 31/12/2011). On a subgroup of patients from the region "Provence Alpes Côte d'Azur", the investigators will analyze the year 2009, and compare to year 2011, to evaluate the impact of theses recommendations.

Detailed Description

Not available

Study Timeline

• Status Verified: 2012-03
• Study First Submitted: 2012-03-27
• Study First Submitted QC: 2012-03-28
• Last Update Submitted: 2012-03-28
• Study First Posted: 2012-03-29
• Last Update Posted: 2012-03-29
• Study Start: 2012-05
• Primary Completion: 2012-11
• Study Completion: 2012-11

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 7000

Inclusion Criteria

• Patients over 18 years, affiliated to RSI, with rheumatoid arthritis treated with at least one DMARDS and/or biologic therapy

Exclusion Criteria

• patients under 18 years
• Patients declared as rheumatoid arthritis without DMARDS or biologic therapy or treated with steroids alone

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patient	Cardiovascular check-up	Patients with rheumatoid arthritis

Primary Outcome Measures

Name	Time	Method
the following items use in the evaluation of the cardiovascular risk factors	at time = 2 years	At least once a years the prescription of at least one of the following items use in the evaluation of the cardiovascular risk factors: * Lipides dosage; * Glycemia; * HbA1C; * Stress test; * Carotid ultra-sonography; * Coronary or lower limbs arteriography; * Heart ultra-sonography; * Cardiology clinic; * Endocrinology clinic

Secondary Outcome Measures

Name	Time	Method
the following items use in the evaluation of the cardiovascular risk factors on the sub population	t=0 and t=2 years	The same criteria of primary criteria but on the sub population of Povence Alpes Cote-d'Azur region a comparison of these criteria in 2009 (before EULAR recommendations ) and in 2011 (after EULAR recommendations)