Skip to main content
Clinical Trials/NCT03602105
NCT03602105
Active, Not Recruiting
N/A

Better Before - Better After: Prehabilitation Program for Older Patients Awaiting Total Hip Replacement. A Randomised Controlled Trial

Oslo Metropolitan University1 site in 1 country103 target enrollmentMarch 1, 2019

Overview

Phase
N/A
Intervention
Not specified
Conditions
Arthritis of Hip
Sponsor
Oslo Metropolitan University
Enrollment
103
Locations
1
Primary Endpoint
Change in gait speed
Status
Active, Not Recruiting
Last Updated
2 years ago

Overview

Brief Summary

Health professions need to prepare for the large increase in the number of older people with OA requiring health services including TJA surgery. Older age and poor physical function influences the postoperative prognosis of TJA. At discharge from hospital after TJA, studies have shown that gait speed can be severely impaired among older patients.

The investigators hypothesize that an exercise program of 6-12 weeks will be beneficial for patients that are undergoing TJA.

Detailed Description

More than 300.000 Norwegians above 20 years of age have osteoarthritis (OA) . There has been a significant increase in the prevalence of OA over the decades. In the United States knee OA affects 19% of adults aged 45 years or older. OA is associated with an extensive high economic and personal burden, largely attributable to the effects of disability, comorbid disease, and the expense of treatment. Given the aging population, the number of total joint arthroplasty procedures (TJA) for hip and knee is likely to increase substantially. In light of poor physical function prior to surgery among older patients and the likelihood of an added decrease during hospitalization and risk of poorer outcome after surgery, it is hypothesised that prehabilitation (preoperative exercise) would improve outcomes after surgery, however evidence for its efficacy is still lacking

Registry
clinicaltrials.gov
Start Date
March 1, 2019
End Date
March 31, 2026
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Oslo Metropolitan University
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Participants 70 years or older living at home with residential address in the county of Oslo or Akershus scheduled for elective primary total hip replacement due to end-stage osteoarthritis.
  • Harris Hip Score \>
  • Participants must also be capable in Norwegian and be able to follow exercise sessions.

Exclusion Criteria

  • Patients with known rheumatoid arthritis or medical contraindications or those who are scheduled for revision of hip arthroplasty
  • Unable to speak and understand the Norwegian language.
  • Patients with neurological disorders affecting gait
  • Medical contraindications for exercise

Outcomes

Primary Outcomes

Change in gait speed

Time Frame: Change measure: Baseline, within one week after intervention, 6 weeks after intervention, 3 months after intervention, 6 months after intervention and 12 months after intervention

40 meters Fast-Paced Walk test

Secondary Outcomes

  • Change in physical function(Change measure: Baseline, within one week after intervention, 6 weeks after intervention, 3 months after intervention, 6 months after intervention and 12 months after intervention)
  • Length of stay in hospital(From date of hospital admission until the date of hospital discharge, assessed up to 12 months)
  • Change in transitional ambulation(Change measure: Baseline, within one week after intervention, 6 weeks after intervention, 3 months after intervention, 6 months after intervention and 12 months after intervention)
  • Change in pain measured with numeric rating scale (NRS)(Change measure: Baseline, within one week after intervention, 6 weeks after intervention and 3 months after intervention)
  • Change in aerobic capacity(1 week before intervention, directly after intervention as well as 6 and 12 weeks after TJA-surgery)
  • Change in the ability to climb stairs(Change measure: Baseline, within one week after intervention, 6 weeks after intervention, 3 months after intervention, 6 months after intervention and 12 months after intervention)
  • Change in Health Status measured with EuroQol-5 dimensions (EQ-5D)(Change measure: Baseline, within one week after intervention, 6 weeks after intervention, 3 months after intervention, 6 months after intervention and 12 months after intervention)

Study Sites (1)

Loading locations...

Similar Trials