The Effect of Oxytocin on Gastric Emptying

Not Applicable

Completed

• Conditions: Dyspepsia; Lack of Satiety
• Interventions: Drug: oxytocin

• Registration Number: NCT01152047
• Lead Sponsor: Skane University Hospital

Brief Summary

The investigators have seen that oxytocin lowers satiety in healthy subjects. Patients with dyspepsia suffers from decreased accommodation and increased satiety postprandially. The investigators now want to examine whether oxytocin may diminish symptoms in these patients.

Detailed Description

Patients will come twice for a slow satiety drinking test. Once they will get saline infusion and once oxytocin 40 mU/min. At the same time they register satiety on a VAS scale.

Study Timeline

• Study Start: 2010-05
• Study First Submitted: 2010-06-23
• Study First Submitted QC: 2010-06-28
• Study First Posted: 2010-06-29
• Status Verified: 2015-04
• Primary Completion: 2015-04
• Study Completion: 2015-04
• Last Update Submitted: 2015-04-06
• Last Update Posted: 2015-04-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

• Dyspepsia

Exclusion Criteria

• Age > 65 years
• Cardiac disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
oxytocin, satiety	oxytocin	Oxytocin is given as infusion to examine if this decreases satiety compared to saline during a drinking test

Primary Outcome Measures

Name	Time	Method
Satiety	2 h	The investigator want to examine whether oxytocin leads to lower satiety scores after intake of the same volume of nutrient

Trial Locations

Locations (1)

Skåne University Hospital; 🇸🇪 Malmö, Sweden