The Effect of Oxytocin on Satiety in Patients With Dyspepsia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 14
- 试验地点
- 1
- 主要终点
- Satiety
研究概览
简要总结
The investigators have seen that oxytocin lowers satiety in healthy subjects. Patients with dyspepsia suffers from decreased accommodation and increased satiety postprandially. The investigators now want to examine whether oxytocin may diminish symptoms in these patients.
详细描述
Patients will come twice for a slow satiety drinking test. Once they will get saline infusion and once oxytocin 40 mU/min. At the same time they register satiety on a VAS scale.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Dyspepsia
排除标准
- •Age > 65 years
- •Cardiac disease
研究组 & 干预措施
oxytocin, satiety
Oxytocin is given as infusion to examine if this decreases satiety compared to saline during a drinking test
干预措施: oxytocin (Drug)
结局指标
主要结局
Satiety
时间窗: 2 h
The investigator want to examine whether oxytocin leads to lower satiety scores after intake of the same volume of nutrient
次要结局
未报告次要终点
研究者
Bodil Ohlsson
Department of Clinical Sciences, Division of Internal Medicine
Skane University Hospital