Pontic Shield and Mineralized Plasmatic Matrix for Ridge Preservation

Not Applicable

Completed

• Conditions: Alveolar Ridge Preservation

• Registration Number: NCT07171879
• Lead Sponsor: Soaad Tolba Mohammed Tolba Badawi

Brief Summary

This study is testing new methods to preserve the jawbone and gum tissue after removing a damaged front tooth. Normally, when a tooth is taken out, the bone and gums in that area shrink, which can make future dental treatment more difficult and affect appearance. A technique called Partial Extraction Therapy (Pontic Shield Technique) keeps part of the tooth root in place to help maintain the natural shape of the bone and gums. Another method, called Mineralized Plasmatic Matrix (MPM), uses a patient's own blood mixed with bone particles to support healing.

In this randomized clinical trial, 56 patients were assigned to one of four groups:

Group I: Tooth extraction only Group II: Tooth extraction with MPM grafting Group III: Pontic shield technique alone Group IV: Pontic shield technique with MPM grafting The main outcome measured was the amount of bone width preserved, using 3D X-rays (CBCT). Other outcomes included bone height and soft-tissue healing over 4 months.

This research will help determine whether the pontic shield technique, with or without MPM, provides better preservation of bone and gum tissue compared to tooth extraction alone.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-09-01
• Primary Completion: 2025-07-01
• Study Completion: 2025-07-01
• Status Verified: 2025-09
• Study First Submitted: 2025-09-06
• Study First Submitted QC: 2025-09-06
• Last Update Submitted: 2025-09-11
• Study First Posted: 2025-09-15
• Last Update Posted: 2025-09-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 56

Inclusion Criteria

• Adults (≥18 years).
• Classified as ASA I (healthy) according to the American Society of Anesthesiologists Physical Status Classification.
• Presence of Type 1 extraction sockets (intact buccal bone and soft tissues).
• Adequate oral hygiene.
• Sufficient inter-arch space for prosthetic rehabilitation.
• Willingness to comply with study protocol and follow-up schedule.

Exclusion Criteria

• Systemic conditions affecting bone metabolism or wound healing (e.g., uncontrolled diabetes, osteoporosis, immunosuppression).
• History of head and neck radiotherapy or bisphosphonate therapy.
• Acute infection or suppuration at the extraction site.
• Severe periodontal disease.
• Root caries or tooth mobility.
• Buccal bone plate loss due to vertical/horizontal root fractures or advanced periodontitis.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Alveolar Ridge Width Change	Baseline (pre- or immediate post-extraction) to 4 months.	Mean changes in alveolar ridge width measured at standardized reference points on cone-beam computed tomography (CBCT) Unit of Measure: millimeters (mm)

Secondary Outcome Measures

Name	Time	Method
Buccal and Palatal Bone Height Change	Baseline to 4 months.	Change in buccal and palatal bone heights measured on CBCT from baseline to 4 months.; Unit of Measure: mm
Soft-Tissue Healing (Wound Healing Index, WHI)	1 week and 4 months post-extraction.	Clinical soft-tissue healing evaluated using the WHI. Unit of Measure: score on 5-point scale with higher values indicating more favorable wound healing.

Trial Locations

Locations (1)

Faculty of Dentistry, Mansoura University; 🇪🇬 Al Mansurah, Dakahlia Governorate, Egypt