Relationship Between the Gut Microbiota and Stress

Completed

• Conditions: Psychological Stress
• Interventions: Other: Observation

• Registration Number: NCT02378610
• Lead Sponsor: Lund University

Brief Summary

The relationship between the gut microbiota and stress is poorly studied in humans. In this study we aim to look for if stressed persons have different levels of key bacterial groups compared to the levels in non-stressed persons.

Detailed Description

The gut microbial flora will be analyzed with molecular genetic methods. Stress will be measured with cortisol levels in saliva and with questionnaire.

Study Timeline

• Study Start: 2015-02
• Study First Submitted: 2015-02-27
• Study First Submitted QC: 2015-03-03
• Study First Posted: 2015-03-04
• Status Verified: 2017-09
• Primary Completion: 2017-09
• Study Completion: 2017-09
• Last Update Submitted: 2017-09-06
• Last Update Posted: 2017-09-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 59

Inclusion Criteria

• Healthy man between 19-35 years old

Exclusion Criteria

• Antibiotic intake
• Gastrointestinal diseases
• Diabetes
• Phsycological diseases
• Tyroid related diseases
• Cardiovascular diseases
• Celiaki
• Cortisone drugs

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Observation in High-stressed	Observation	Saliva and fecal samples will be collected from High-stressed persons
Observation in Low-stressed	Observation	Saliva and fecal samples will be collected from Low-stressed persons

Primary Outcome Measures

Name	Time	Method
Markers of the gut microbiota	May 2015-January 2016

Secondary Outcome Measures

Name	Time	Method
Markers of stress	April 2015-January 2016

Trial Locations

Locations (1)

Lund University; 🇸🇪 Lund, Sweden