Cognitive-Behavioral Therapy for Irritability in Adolescents With High Functioning Autism Spectrum Disorder

Not Applicable

Completed

• Conditions: Asperger's Disorder; Autism Spectrum Disorder (ASD; Autism; Pervasive Developmental Disorder (PDD-NOS)
• Interventions: Behavioral: Cognitive-Behavioral Therapy (CBT) for Irritability

• Registration Number: NCT01631851
• Lead Sponsor: Yale University

Brief Summary

In addition to the core symptoms, children and adolescents with Autism Spectrum Disorder (ASD) often exhibit disruptive behavior problems including irritability, tantrums, noncompliance, and aggression. This is a pilot study of Cognitive-Behavioral Therapy, also known as Anger Control Training, in adolescents with high-functioning ASD. CBT teaches children to recognize antecedents and consequences of problem behavior and to use emotion regulation and problem-solving skills to reduce irritability, aggression and noncompliance. This form of CBT has been well-studied in typically developing children with disruptive behavior and we are investigating if this treatment can be feasible and helpful, with appropriate modifications, for irritability and disruptive behavior in ASD.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-05
• Study First Submitted: 2012-06-27
• Study First Submitted QC: 2012-06-27
• Study First Posted: 2012-06-29
• Primary Completion: 2013-04-23
• Study Completion: 2013-04-23
• Status Verified: 2023-11
• Last Update Submitted: 2023-11-15
• Last Update Posted: 2023-11-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 9

Inclusion Criteria

• DSM-IV diagnosis of autistic disorder, Asperger's disorder, or PDD-NOS
• presence of disruptive behaviors such as irritability and anger outbursts
• IQ above 80
• Unmedicated or on stable medication

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Exclusion Criteria

• medical or psychiatric condition that would require alternative treatment

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Cognitive behavior therapy	Cognitive-Behavioral Therapy (CBT) for Irritability	-

Primary Outcome Measures

Name	Time	Method
ABC Irritability Scale	1 week	Parent rating of irritability and disruptive behavior that has been often used in studies with children with ASD

Trial Locations

Locations (1)

Yale Child Study Center; 🇺🇸 New Haven, Connecticut, United States