Echocardiographic and Laboratory Findings in Hemodynamic Monitoring of Shocked Patients

Not yet recruiting

• Conditions: Shock

• Registration Number: NCT06343519
• Lead Sponsor: Assiut University

Brief Summary

Shocked patients require prompt and accurate assessment of their hemodynamic status to guide appropriate management. Echocardiography is a valuable tool for assessing cardiac function, while laboratory parameters such as mixed venous oxygen saturation and arterial blood lactate provide insights into tissue perfusion and oxygen metabolism. This study aims to compare echocardiographic findings, including cardiac index, speckle tracking parameters, and tissue Doppler indices, with laboratory findings in the evaluation of hemodynamic monitoring in shocked patients.

Detailed Description

Shocked individuals necessitate expeditious and precise evaluation of their hemodynamic condition to direct appropriate treatment. The utilization of echocardiography is an invaluable method for appraising cardiac function, while the inclusion of laboratory parameters such as mixed venous oxygen saturation and arterial blood lactate offers valuable insights into tissue perfusion and oxygen metabolism. The primary objective of this study is to compare the echocardiographic discoveries, which encompass the assessment of cardiac index, speckle tracking parameters, and tissue Doppler indices, with the laboratory findings in the comprehensive assessment of hemodynamic monitoring in individuals experiencing shock. The purpose of this investigation is to delineate the correlation between echocardiographic and laboratory assessments in order to enhance our understanding of hemodynamic status in patients who are in a state of shock.

Study Timeline

• Status Verified: 2024-03
• Study First Submitted: 2024-03-06
• Study First Submitted QC: 2024-03-30
• Last Update Submitted: 2024-03-30
• Study First Posted: 2024-04-02
• Last Update Posted: 2024-04-02
• Study Start: 2024-05
• Primary Completion: 2026-03
• Study Completion: 2026-05

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Patients diagnosed with shock based on clinical criteria (e.g., hypotension, signs of tissue hypoperfusion) requiring hemodynamic monitoring.
• Patients age > 18 year old.

Exclusion Criteria

• Patients with pre-existing cardiac conditions affecting echocardiographic parameters, those receiving mechanical circulatory support.
• Patients with contraindications to echocardiography or blood sampling.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in Shock Status After Fluid Therapy Based on Echocardiographic Assessment of Fluid Responsiveness	24 hours	Change in shock status will be assessed 24 hours after initiation of fluid therapy by echocardiographic evaluation of cardiac index in liters per minute per square meter (L/min/m2).