Validity of novel urinary biomarkers of flavan-3-ol intake in healthy participants: A randomised, 5-way cross-over trial

niversity of Western Australia0 个研究点目标入组 16 人开始时间: 2019年11月12日最近更新: 2023年1月23日

适应症

试验速览

暂无简介。

•Adults unable to consent
•Body mass index less than 18.5 or greater than 30 kg/m2
•Systolic blood pressure less than 150 mmHg
•Diastolic BP less than 100 mmHg
•Diagnosed diabetes
•Current or recent (less than 12 months) smoking
•History of cardiovascular or peripheral vascular disease
•Use of blood pressure lowering or cholesterol lowering medication
•Psychiatric illness or other major illnesses such as cancer
•Alcohol intake greater than 210 g per week for women and greater than 280 g per week for men
•Women who are lactating, pregnant or wishing to become pregnant during the study.
•Inability to attend clinic/office visits
•Use of antibiotics (within previous 3 months)
•Inability or unwillingness to follow the study protocol
•Any dietary allergies to cocoa, tea and apples or any ingredients in the standardised
•GI tract disorders, previous GI surgery (except appendectomy)
•Self-reported malabsorption (e.g. difficulty digesting or absorbing nutrients from food, potentially leading to bloating, cramping or gas)
•Diarrhoea within the last 3 months
•Vegetarian, Vegan, food faddists, individuals using non-traditional diets, on a weight loss diet or individuals following diets with significant deviations from the average diet
•Currently participating in another clinical or dietary intervention study

发起方

niversity of Western Australia