Ridge Augmentation Using Allograft Particles Hydrated With or Without Recombinant Human Platelet-Derived Growth Factor

Not Applicable

Recruiting

• Conditions: Dental Implant; Bone Loss

• Registration Number: NCT04954664
• Lead Sponsor: University of Alabama at Birmingham

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-6-29
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 44

Inclusion Criteria

Inclusion Criteria:<br><br> - English speaking<br><br> - At least 18 years old<br><br> - Must be a patient of the UAB Dental School<br><br> - Able to read and understand informed consent document<br><br> - Need for implants to replace missing tooth or teeth in at least one quadrant of the<br> mouth.<br><br> - Insufficient alveolar ridge width for endosseous implant placement defined as 5mm or<br> less as determined by bone sounding and cone beam computed tomography (CBCT) scan.<br><br>Exclusion Criteria:<br><br> - Non-English speaking<br><br> - Less than 18 years old<br><br> - Smokers/tobacco users (>10 cigarettes/day)<br><br> - Patients with systemic pathologies or conditions contraindicating oral surgical<br> procedures or adversely affecting wound healing<br><br> - Patient is a poor compliance risk (i.e., poor oral hygiene, history of alcohol or<br> drug abuse)<br><br> - Vertical loss of bone at edentulous ridge.

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Quantitative histomorphometric evaluation of new bone formation 4 months after GBR

Secondary Outcome Measures

Name	Time	Method
Quantitative two- and three-dimensional radiographic comparison of dimensional changes 4 months using cone beam computed tomography (CBCT) and a virtual implant planning software, coDiagnostiX™