CaRe High - Cascade Screening and Registry for High Cholesterol

Recruiting

• Conditions: E78.0; Pure hypercholesterolaemia

• Registration Number: DRKS00011824
• Lead Sponsor: D-A-CH-Gesellschaft Prävention von Herz-Kreislauf-Erkrankungen e.V.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-03-06
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 3000

Inclusion Criteria

LDL-cholesterol >190mg/dl without lipid-lowering therapy; cholesterol >290 mg/dl without lipid-lowering therapy; tendon xanthomas; positive family history for hypercholesterolemia; positive family history for myocard infarct before the age of 50 for grand-parents, uncle, aunts or before the age of 60 for parents, siblings and children; first and second degree relatives of patients with FH

Exclusion Criteria

refusal of written consent of participation in the study; obvious impairment of cognitive functions; decompensated, acute psychiatric diseases; acute non-cardio-vascular disease, non-cardio-vascular surgeries within the last three months, chronic non-cardiac diseases (e.g. chronic kidney failure, rheumatoide arthritis, cancer during the last 5 years); people, not able to understand the meaning of the study

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
identification of patients with FH<br>and establishment of a patient registry for FH

Secondary Outcome Measures

Name	Time	Method
evaluation of the acceptance and effectivity of a cascade screening for FH in Germany;<br>Capture of the situation of care of FH patients in Germany