The improvement effect of probiotics using tablet containing Lactobacillus salivarius WB21 on bad breath

Not Applicable

Completed

• Conditions: Oral malodor; Signs and Symptoms; Halitosis

• Registration Number: ISRCTN74332440
• Lead Sponsor: Fukuoka Dental College (Japan)

Brief Summary

2014 results in https://pubmed.ncbi.nlm.nih.gov/24556493/ (added 17/12/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2011-09-30
• Study Start: 2013-01-10
• Last Update Posted: 5 January 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 26

Inclusion Criteria

1. 26 eligible patients (22 females and four males; mean age, 43.5 ± 11.5 years; age range, 22?67 years)
2. Oral malodor above a questionable level (OLT score = 1.5)
3. Not currently visiting a dentist for treatment
4. No acute symptoms requiring immediate oral cavity treatment
5. No use of probiotic supplements
6. No antibiotic use within the last month
7. No daily smoking habit
8. No systemic illness
9. No adverse reactions to lactose or fermented milk products

Exclusion Criteria

Does not meet inclusion criteria

56 were excluded: 48 did not meet the inclusion criteria, three refused to participate, and five had personality traits that were considered difficult for adherence to the protocol.

Study & Design

• Study Type: Interventional
• Study Design: Not specified