跳至主要内容
临床试验/JPRN-UMIN000053277
JPRN-UMIN000053277已完成Unknown

Multiple oral antibiotics therapy for induction and maintenance of ulcerative colitis - Multiple oral antibiotics therapy for ulcerative colitis

Juntendo University Graduate School of Medicine0 个研究点目标入组 320 人开始时间: 2024年1月5日最近更新:
适应症

试验速览

阶段
Unknown
状态
已完成
发起方
入组人数
320

研究概览

简要总结

The compliance rate was 95.7%. The response rate and remission rate were 75.2% and 30.9% at completion, 62.7% and 29.6% at 3 months, 48.2% and 27.7% at 6 months, 37.9% and 24.4% at 9 months, 35.4% and 24.4% at 12 months, respectively. The most frequent adverse events were diarrhea and fever. No life-threatening adverse events were observed during the trial.

研究设计

研究类型
Interventional

入排标准

年龄范围
15years-old 至 ot applicable(—)
性别
All

入选标准

  • 未提供

排除标准

  • Exclusion criteria were penicillin allergy, administration of antibiotics agents within 2 weeks of study entry, ongoing biologic therapy, pregnancy, cancer and other serious comorbid illness. Patients who had stool pathogens including Clostridium difficile, Salmonellae, pathogenic Escherichia coli were also excluded.

研究者

发起方
Juntendo University Graduate School of Medicine

相似试验