Seven-day Ambulatory Blood Pressure Monitoring and CAVI in the Prevention of Cardiovascular Diseases
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 171
- 试验地点
- 1
- 主要终点
- The risk rate of incorrect patient classification based on night-to-day ratio specification from singular 24-h ABPM in comparison to the results of 7-day ABPM monitoring.
研究概览
简要总结
Specify the risk rate of incorrect patient classification based on night-to-day ratio specification from singular 24-h ABPM in comparison to the results of 7-day ABPM monitoring
详细描述
The subjects in the study are divided into 4 groups:
group 1 (40 healthy men and women without exercise); group 2 (40 healthy exercise-training men and women); group 3 (40 patients with ischemic coronary artery disease without exercise); and group 4 (51 patients with ischemic coronary artery disease following cardiovascular rehabilitation).
The subject of the evaluation is the percentage rate of incorrect subject classification (dipper, non-dipper, extreme dipper, and risers) based on the mean blood pressure values for 7 days and from seven independent 24-hour cycles (the mean value mode).
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy volunteers (without any disease, including the cardiovascular ones, and without any kind of treatment)
- •Patients with chronic ischemic coronary artery disease
- •Patients treated with ACE inhibitors, beta-blockers or statins.
- •To visit routinely in the health centres where the study is carried out
排除标准
- •Age under 18 years,
- •Pregnant, or breast-feeding,
- •Patients on dialysis or being followed by nephrology,
- •Severe physical or cognitive limitations,
- •Intolerance to the method of measurement
研究组 & 干预措施
Group 1
Healthy volunteers without exercise
干预措施: Ambulatory blood pressure monitoring (Other)
Group 2
Healthy exercise-training volunteers
干预措施: Ambulatory blood pressure monitoring (Other)
Group 2
Healthy exercise-training volunteers
干预措施: Combined aerobic-resistance exercise (Other)
Group 3
Patients with ischemic coronary artery disease without exercise
干预措施: Ambulatory blood pressure monitoring (Other)
Group 4
Patients with ischemic coronary artery disease following cardiovascular rehabilitation
干预措施: Ambulatory blood pressure monitoring (Other)
Group 4
Patients with ischemic coronary artery disease following cardiovascular rehabilitation
干预措施: The cardiovascular exercise (Other)
结局指标
主要结局
The risk rate of incorrect patient classification based on night-to-day ratio specification from singular 24-h ABPM in comparison to the results of 7-day ABPM monitoring.
时间窗: 1 - 7 days
Primary outcome was to specify the risk rate of incorrect patient classification based on night-to-day ratio specification from singular 24-h ABPM in comparison to the results of 7-day ABPM monitoring. The percentage of blood pressure drop at night expressed by night-to-day ratio (dippers, non-dippers, extreme dippers, reverse dippers) can be specified much more accurately on the basis of 7-day ABPM values. ABPM restricted to 24 h, as currently practiced, does not yield a sufficiently reliable estimate of the night-to-day ratio for a classification in terms of dipping. Extending monitoring to 7 days accounts for the large day-to-day variability in the night-to-day ratio, and may yield a more reliable diagnosis of blood pressure variability.
次要结局
- Optimalization of the blood pressure diagnostic through comparing of 24 hours and 7 days monitoring.(1 - 7 days)