Construction of biological sample bank and information platform for peri-implant health

Phase 1

Completed

Conditions: Peri-implant disease

Registration Number: ChiCTR2400088882

Lead Sponsor: Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: Not specified

Inclusion Criteria

(1) The patients were required to be at least 18 years of age and able to sign the informed consent; (2) partially edentulous patients requiring at least two consecutive implants for a 2–3 crown bridge in each posterior mandible or maxilla.; (3) Bone volumes were required to allow the placement of implants at least 8 mm in length (bone height at least 11 mm from compromised anatomical structures, because the implants were placed 1 mm subcrestally) and 4.0–4.5 mm in width (7 mm wide bone crest), without bone regeneration procedures; (4) absence of oral mucosal disease and oral infection; (5) implants with specific diameter (Astra TX); (6) The required minimum vertical supracrestal soft tissue thickness was 2 mm.; (7) willingness to participate in the present study. (8) periodontitis has already be controlled (9) Likewise, the patients were required to present healed bone for at least 3 months and without infection

Exclusion Criteria

(1) Heavy smokers (>10 cigarettes/day); (2) natural teeth adjacent to surgical area affected by untreated periodontal or endodontic infections ; (3) uncontrolled periodontitis(full-mouth plaque score >20%, full-mouth bleeding score >25%,residual pocket depth >5 mm); (4) the enrolled patients were required to have no systemic conditions contraindicating implant surgery (immunosuppression, irradiation of the head and/or neck, patients treated with intravenous amino-bisphosphonates, uncontrolled diabetes, pregnancy or lactation, addiction to alcohol or drugs, psychiatric problems); (5) a lack of primary implant stability or the need for a simultaneous hard tissue grafting or two-stage implant surgery. (6) None of the recruited patients had received antibiotics in the last three months prior to examination. (7) Patients unable to complete follow-up, and implant failures, were excluded.