JPRN-UMIN000042666Completed未知
Study on the effect of plant-derived bioactive components on cognitive functions in the healthy elderly subjects. - Study on the effect of plant-derived bioactive components on cognitive functions in the healthy elderly subjects.
Innovation Division, Kagome Co., Ltd.0 sites144 target enrollmentStarted: December 5, 2020Last updated:
Conditions
Trial Snapshot
- Phase
- 未知
- Status
- Completed
- Sponsor
- Enrollment
- 144
Study Overview
Brief Summary
he SFN group showed improvement in processing speed and a decrease in negative mood compared to the placebo group. In addition, the SFN group exhibited a higher SFN-N-acetyl-L-cysteine (NAC) level compared to the placebo group. However, there were no significant results in other biomarkers of oxidant stress, inflammation, or neural plasticity.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 60years-old to 81years-old (—)
- Sex
- All
Inclusion Criteria
- Not provided
Exclusion Criteria
- •1. Those suffering from mental illness, diabetes, neurological disease, heart disease (cardiac disease), or other serious illnesses. 2. Those who are taking medicine that affect cognitive function (eg benzodiazepines, antidepressants, central nervous system medicine) 3. Those who have a history of serious illnesses in the past and are judged to have problems participating in this study. 4. Those who have a score of 26 points or less in the MMSE (Mini Mental State Examination), a screening test for dementia. 5. Those who have a Geriatric Depression Scale of 5 or more, which is a test to check the degree of depression. 6. Those who have a score of 12 points or less on the frontal assessment battery at bedside (FAB), a frontal lobe function test. 7. Those who have a score of less than 85 in the simple IQ estimation test by JART 8. Those who may have allergies to food (especially those who are allergic to broccoli, milk, eggs, wheat, buckwheat, peanuts, shrimp, crabs) 9. Those who have a drinking habit of more than 60 g of pure alcohol as average daily drinking amount on weekly basis. 10. Those who are currently participating in other studies, or who have participated in other studies within 2 months. 11. Those who cannot refrain from using medicines and health foods (including supplements, foods for specified health use, foods with health claims, aojiru, energy drinks) that may affect the test values, during the test period. 12. Those who are unable to intake the test food or placebo as instructed during the test period, or those who cannot fill in the life diary 13. Others who are determined by the principal investigator as inappropriate subjects.
Investigators
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