Comparison between Lidocaine Spray and Cryotherapy for Pain Reduction during Amniocentesis in Second Trimester Pregnancy

Phase 4

Completed

• Conditions: Pain during amniocentesis at gestational aged 15-20 weeks; Pregnancy; Amniocentesis; Pain; Xylocaine spray; Cryotherapy

• Registration Number: TCTR20210331005
• Lead Sponsor: Research unit, Thammasat university

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-03-31
• Study Completion: 2021-12-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 330

Inclusion Criteria

1.Pregnancy requiring amniocentesis at gestational aged 15-20 weeks
2. Pregnancy who didn't present of fetal anomaly from ultrasound

Exclusion Criteria

1.Multiple pregnancies
2.Contraindication for amniocentesis such as threatened abortion
3. Change puncture site for amniocentesis after sprayed the xylocaine spay and placed the cool packed due to fetal movement
4.More than one attempt of needle insertion
5.History for lidocaine allergy
6.Infection at abdominal wall
7.Psychosis
8. Denied for volunteers

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain during amniocentesis during procedure visual analog scale (VAS)

Secondary Outcome Measures

Name	Time	Method
Pain after procedure 15, 30 minutes after procedure visual analog scale (VAS)