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临床试验/NCT04943263
NCT04943263Unknown不适用

A Comparison of Body Temperature Measured From the Cuff Surface of the Endotracheal Tube and Core Temperature in Living Donor Liver Transplantation

Seoul National University Hospital1 个研究点 分布在 1 个国家目标入组 22 人开始时间: 2021年8月13日最近更新:
适应症
干预措施

试验速览

阶段
不适用
入组人数
22
试验地点
1
主要终点
Comparison of temperature from the cuff surface of the endotracheal tube and esophageal temperature

研究概览

简要总结

The purpose of this study is to compare the temperature measured from the cuff surface of the endotracheal tube and core temperature measured at the esophagus in living donor liver transplantation recipients.

详细描述

Hypothermia occurs frequently in patients undergoing surgery and is known to be related with many postoperative complications. Patients undergoing living donor liver transplantation are usually monitored using an esophageal stethoscope. However, because patients with liver cirrhosis have the risk of variceal bleeding, placement of an esophageal stethoscope can increase the risk of bleeding.

There have been previous reports that temperature monitoring at the cuff surface of an endotracheal tube is not only safe but also provides accurate and reliable data during mild hypothermia after cardiac arrest.

This study compares the temperature measured from the cuff surface of the endotracheal tube and core temperature measured at the esophagus and additionally core temperature measured by a pulmonary artery catheter. The study participants are intubated with an endotracheal tube that has a temperature sensor at the cuff surface of the tube. The rest of the procedure is done according to Seoul National University Hospital's protocol for liver transplantation: an esophageal stethoscope is placed for temperature monitoring and a central line is placed with a Multi-Access lumen Catheter and a pulmonary artery catheter is placed. The temperature measurements from the endotracheal tube and measurements from the esophageal stethoscope are compared at the following 5 phases: 1. preanhepatic phase, 2. anhepatic phase 1 (recipient hepatectomy - IVC clamping), 3. anhepatic phase 2 (IVC clamping - reperfusion), 4. Reperfusion phase, 5. Neohepatic phase.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Other
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • routine living donor liver transplantation recipients needing pulmonary artery catheterization who have been informed and given consent

排除标准

  • 未提供

研究组 & 干预措施

Tracheal Temperature

Experimental

Intubation done with a temperature sensor located on the cuff surface of the endotracheal tube

干预措施: Tracheal Temperature (Other)

结局指标

主要结局

Comparison of temperature from the cuff surface of the endotracheal tube and esophageal temperature

时间窗: Phase 5 (neohepatic): 1 hour after Reperfusion

temperature

次要结局

  • Comparison of temperature from the cuff surface of the endotracheal tube and temperature measured at the pulmonary artery catheter(Phase 5 (neohepatic): 1 hour after Reperfusion)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Hee-Soo Kim

Professor

Seoul National University Hospital

研究点 (1)

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